The Afa/Dr Adhesins of Diffusely Adhering Escherichia coli Stimulate Interleukin-8 Secretion, Activate Mitogen-Activated Protein Kinases, and Promote Polymorphonuclear Transepithelial Migration in T84 Polarized Epithelial Cells

Afa/Dr diffusely adhering Escherichia coli (Afa/Dr DAEC) strains cause symptomatic urinary tract and intestinal infections. The proinflammatory effects of Afa/Dr DAEC strains in vitro have been not investigated to date. In the present study, we used confluent polarized monolayers of intestinal cell...

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Bibliographic Details
Main Authors: Bétis, Fréderic, Brest, Patrick, Hofman, Véronique, Guignot, Julie, Bernet-Camard, Marie-Françoise, Rossi, Bernard, Servin, Alain, Hofman, Paul
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2003
Subjects:
Host Response and Inflammation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC148852/
https://ncbi.nlm.nih.gov/pubmed/12595416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.3.1068-1074.2003
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