Intrapulmonary Expression of Macrophage Inflammatory Protein 1α (CCL3) Induces Neutrophil and NK Cell Accumulation and Stimulates Innate Immunity in Murine Bacterial Pneumonia

Macrophage inflammatory protein 1α (MIP-1α) (CCL3) is an important mediator of leukocyte recruitment and activation in a variety of inflammatory states, including infection. A recombinant human type 5 adenovirus containing the murine MIP-1α cDNA (AdMIP-1α) was constructed to determine the effect of...

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Bibliographic Details
Main Authors: Zeng, Xianying, Moore, Thomas A., Newstead, Michael W., Hernandez-Alcoceba, Ruben, Tsai, Wan C., Standiford, Theodore J.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2003
Subjects:
Host Response and Inflammation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC148850/
https://ncbi.nlm.nih.gov/pubmed/12595446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.3.1306-1315.2003
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