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The Yeast Heat Shock Transcription Factor Changes Conformation in Response to Superoxide and Temperature

In vitro DNA-binding assays demonstrate that the heat shock transcription factor (HSF) from the yeast Saccharomyces cerevisiae can adopt an altered conformation when stressed. This conformation, reflected in a change in electrophoretic mobility, requires that two HSF trimers be bound to DNA. Single...

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Bibliographic Details
Main Authors: Lee, Sengyong, Carlson, Tage, Christian, Noah, Lea, Kristi, Kedzie, Jennifer, Reilly, James P., Bonner, J. José
Format: Artigo
Language:Inglês
Published: The American Society for Cell Biology 2000
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC14881/
https://ncbi.nlm.nih.gov/pubmed/10793149
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