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The DNA-binding domain of human c-Abl tyrosine kinase promotes the interaction of a HMG chromosomal protein with DNA.

The biological activity of the c-Abl protein is linked to its tyrosine kinase and DNA-binding activities. The protein, which plays a major role in the cell cycle response to DNA damage, interacts preferentially with sequences containing an AAC motif and exhibits a higher affinity for bent or bendabl...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
I whakaputaina i:Nucleic Acids Res
Ngā kaituhi matua: David-Cordonnier, M H, Payet, D, D'Halluin, J C, Waring, M J, Travers, A A, Bailly, C
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Oxford University Press 1999
Ngā marau:
Urunga tuihono:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148790/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10325413/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.11.2265
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