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An essential surface motif (WAQKW) of yeast RNA triphosphatase mediates formation of the mRNA capping enzyme complex with RNA guanylyltransferase.

Saccharomyces cerevisiae RNA triphosphatase (Cet1p) and RNA guanylyltransferase (Ceg1p) interact in vivo and in vitro to form a bifunctional mRNA capping enzyme complex. Cet1p binding to Ceg1p stimulates the guanylyltransferase activity of Ceg1p. Here we localize the guanylyltransferase-binding and...

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Udgivet i:Nucleic Acids Res
Principais autores: Ho, C K, Lehman, K, Shuman, S
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 1999
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148765/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10572165/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.24.4671
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