Nuclease footprint analyses of the interactions between RNase P ribozyme and a model mRNA substrate.
RNase P ribozyme cleaves an RNA helix substrate which resembles the acceptor stem and T-stem structures of its natural tRNA substrate. By linking the ribozyme covalently to a sequence (guide sequence) complementary to a target RNA, the catalytic RNA can be converted into a sequence-specific ribozyme...
Uloženo v:
| Vydáno v: | Nucleic Acids Res |
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| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Oxford University Press
1999
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148747/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10556315/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.23.4590 |
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