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Nitric oxide-induced damage to mtDNA and its subsequent repair.

Mutations in mitochondrial DNA (mtDNA) have recently been associated with a variety of human diseases. One potential DNA-damaging agent to which cells are continually exposed that could be responsible for some of these mutations is nitric oxide (NO). To date, little information has been forthcoming...

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Autores principales: Grishko, V I, Druzhyna, N, LeDoux, S P, Wilson, G L
Formato: Artigo
Lenguaje:Inglês
Publicado: 1999
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC148736/
https://ncbi.nlm.nih.gov/pubmed/10536162
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