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Genetic association between the APOE*4 allele and Lewy bodies in Alzheimer disease

Objective: To explore the association between APOE*4 and pathologically confirmed cases of the Lewy body (LB) variant of Alzheimer disease (AD). Methods: With use of α-synuclein (AS) immunohistochemistry, LBs were detected in 74 of 131 (56.5%) of the AD + LB cases; the remaining 57 cases (43.5%) did...

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Detalhes bibliográficos
Main Authors: Tsuang, D.W., Wilson, R.K., Lopez, O.L., Luedecking-Zimmer, E.K., Leverenz, J.B., DeKosky, S.T., Kamboh, M.I., Hamilton, R.L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1487185/
https://ncbi.nlm.nih.gov/pubmed/15699383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/01.WNL.0000150892.81839.D1
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