Multi-forms of human MTH1 polypeptides produced by alternative translation initiation and single nucleotide polymorphism.

The human MTH1 gene for 8-oxo-7,8-dihydrodeoxyguanosine triphosphatase, produces seven types (types 1, 2A, 2B, 3A, 3B, 4A and 4B) of mRNAs. The B-type mRNAs with exon 2b-2c segments have three additional in-frame AUGs in their 5' regions. We report here that these transcripts produce three forms of...

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Publicado en:	Nucleic Acids Res
Autores principales:	Oda, H, Taketomi, A, Maruyama, R, Itoh, R, Nishioka, K, Yakushiji, H, Suzuki, T, Sekiguchi, M, Nakabeppu, Y
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Oxford University Press 1999
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148714/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10536140/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.22.4335
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