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Imidazole-imidazole pair as a minor groove recognition motif for T:G mismatched base pairs.

The T:G mismatched base pair is associated with many genetic mutations. Understanding its biological consequences may be aided by studying the structural perturbation of DNA caused by a T:G base pair and by specific probing of the mismatch using small molecular ligands. We have shown previously that...

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Autors principals: Yang, X L, Hubbard , R B, Lee, M, Tao, Z F, Sugiyama, H, Wang, A H
Format: Artigo
Idioma:Inglês
Publicat: 1999
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC148692/
https://ncbi.nlm.nih.gov/pubmed/10518609
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