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Massive parallel analysis of DNA-Hoechst 33258 binding specificity with a generic oligodeoxyribonucleotide microchip.

A generic oligodeoxyribonucleotide microchip was used to determine the sequence specificity of Hoechst 33258 binding to double-stranded DNA. The generic microchip contained 4096 oxctadeoxynucleo-tides in which all possible 4(6)= 4096 hexadeoxy-nucleotide sequences are flanked on both the 3'- and 5'-...

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Publicat a:Nucleic Acids Res
Autors principals: Drobyshev, A L, Zasedatelev, A S, Yershov, G M, Mirzabekov, A D
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 1999
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148679/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10497276/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.20.4100
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