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Delayed DNA joining at 3' mismatches by human DNA ligases.

Repair synthesis catalysed by DNA polymerase beta at 1 nt gaps occurs in the main pathway of mammalian base excision repair. DNA polymerase beta has no exonucleolytic proof-reading ability, and exhibits high error frequency during DNA synthesis. Consequently, continuous correction of endogenous DNA...

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Détails bibliographiques
Publié dans:Nucleic Acids Res
Auteurs principaux: Bhagwat, A S, Sanderson, R J, Lindahl, T
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 1999
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148670/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10497267/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.20.4028
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