Accurate selection of a 5' splice site requires sequences within fibronectin alternative exon B.
Inclusion of fibronectin alternative exon B in mRNA is developmentally regulated. Here we demonstrate that exon B contains two unique purine-rich sequence tracts, PRE1 and PRE2, that are important for proper 5' splice site selection both in vivo and in vitro. Targeted mutations of both PREs decrease...
Guardat en:
| Publicat a: | Nucleic Acids Res |
|---|---|
| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
1999
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148659/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10481035/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.19.3945 |
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