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The inefficient replication origin from yeast ribosomal DNA is naturally impaired in the ARS consensus sequence and in DNA unwinding.

Ribosomal DNA (rDNA) replication origins of Saccharomyces cerevisiae are known to function inefficiently, both in the context of the tandem rDNA repeats in the chromosome and as single copy autonomously replicating sequences (ARSs) in plasmids. Here we examined components of the rDNA ARS that might...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Miller, C A, Umek, R M, Kowalski, D
Format: Artigo
Language:Inglês
Published: Oxford University Press 1999
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148656/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10481032/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.19.3921
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