The 5'-untranslated region of GM-CSF mRNA suppresses translational repression mediated by the 3' adenosine-uridine-rich element and the poly(A) tail.

Granulocyte-macrophage colony stimulating factor (GM-CSF) mRNA levels are controlled post-transcriptionally by the 3'-untranslated region (UTR) adenosine-uridine-rich element (ARE). In untransformed, resting cells, the ARE targets GM-CSF mRNA for rapid degradation, thereby significantly suppressing...

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Dades bibliogràfiques

Publicat a:	Nucleic Acids Res
Autors principals:	Jarzembowski, J A, Rajagopalan, L E, Shin, H C, Malter, J S
Format:	Artigo
Idioma:	Inglês
Publicat:	Oxford University Press 1999
Matèries:	Research Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148620/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10471734/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.18.3660
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