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Differential subcellular localization of human MutY homolog (hMYH) and the functional activity of adenine:8-oxoguanine DNA glycosylase.

The post-replicative adenine:8-oxo-7,8-dihydroguanine (GO) mismatch is crucial for G:C to T:A transversion. This mismatch is corrected by Escherichia coli MutY which excises the adenine from A:GO. A candidate gene coding for the human counterpart of MutY has been cloned as hMYH. However, the functio...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Takao, M, Zhang, Q M, Yonei, S, Yasui, A
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 1999
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148617/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10471731/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.18.3638
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