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The identification of nuclear proteins that bind the homopyrimidine strand of d(GA.TC)n DNA sequences, but not the homopurine strand.

Alternating d(GA.TC)(n)DNA sequences, which are abundant in eukaryotic genomes, can form altered DNA structures. Depending on the environmental conditions, the formation of (GA.GA) hairpins or [C+T(GA.TC)] and [GA(GA.TC)] intramolecular triplexes was observed in vitro. In vivo, the formation of thes...

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Detalles Bibliográficos
Main Authors: García-Bassets, I, Ortiz-Lombardía, M, Pagans, S, Romero, A, Canals, F, Avil s, F X, Azorín, F
Formato: Artigo
Idioma:Inglês
Publicado: 1999
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC148559/
https://ncbi.nlm.nih.gov/pubmed/10454633
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