Conversion of a DNA ligase into an RNA capping enzyme.
In eukaryotes, newly synthesised mRNA is 'capped' by the addition of GMP to the 5" end by RNA capping enzymes. Recent structural studies have shown that RNA capping enzymes and DNA ligases have similar protein folds, suggesting a conserved catalytic mechanism. To explore these similarities we have p...
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| Udgivet i: | Nucleic Acids Res |
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| Hovedforfatter: | |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
1999
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148557/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10454631/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.16.3253 |
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