p300/CBP is required for transcriptional induction by interleukin-4 and interacts with Stat6.

Interleukin-4 (IL-4) induces tyrosine phosphorylation of the latent transcription factor Stat6, which mediates the transcriptional responses of IL-4. The transactivation domain of Stat6 has recently been mapped to the C-terminal region of Stat6. We have investigated the mechanism by which Stat6, thr...

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Bibliographic Details
Main Authors: Gingras, S, Simard, J, Groner, B, Pfitzner, E
Format: Artigo
Language:Inglês
Published: 1999
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC148481/
https://ncbi.nlm.nih.gov/pubmed/10373589
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