DNA minor groove recognition of a non-self-complementary AT-rich sequence by a tris-benzimidazole ligand.

The crystal structure of the non-self-complementary dodecamer DNA duplex formed by d(CG[5BrC]ATAT-TTGCG) and d(CGCAAATATGCG) has been solved to 2.3 A resolution, together with that of its complex with the tris-benzimidazole minor groove binding ligand TRIBIZ. The inclusion of a bromine atom on one s...

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Veröffentlicht in:	Nucleic Acids Res
Hauptverfasser:	Aymami, J, Nunn, C M, Neidle, S
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Oxford University Press 1999
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148478/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10373586/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.13.2691
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