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Overexpression of inducible heat shock protein 70 and its mutants in astrocytes is associated with maintenance of mitochondrial physiology during glucose deprivation stress

Wild-type inducible Hsp70 (WT) and 2 folding deficient mutants protect the brain against focal cerebral ischemia in vivo and brain cells from oxygen–glucose deprivation (OGD) in vitro, but the protective mechanisms remain unclear. Mitochondria are central to both normal physiological function and th...

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Autori principali: Ouyang, Yi-Bing, Xu, Li-Jun, Sun, Yun-Juan, Giffard, Rona G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cell Stress Society International 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1484518/
https://ncbi.nlm.nih.gov/pubmed/16817324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1379/CSC-182R.1
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