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The PC6B Cytoplasmic Domain Contains Two Acidic Clusters That Direct Sorting to Distinct trans-Golgi Network/Endosomal Compartments
The mammalian proprotein convertases (PCs) are a family of secretory pathway enzymes that catalyze the endoproteolytic maturation of peptide hormones and many bioactive proteins. Two PCs, furin and PC6B, are broadly expressed and share very similar cleavage site specificities, suggesting that they m...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The American Society for Cell Biology
2000
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC14845/ https://ncbi.nlm.nih.gov/pubmed/10749928 |
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