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An mRNA sequence derived from a programmed frameshifting signal decreases codon discrimination during translation initiation

Sequences and structures in the mRNA can alter the accuracy of translation. In some cases, mRNA secondary structures like hairpin loops or pseudoknots can cause frequent errors of translational reading frame (programmed frameshifting) or misreading of termination codons as sense (nonsense readthroug...

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Detalhes bibliográficos
Main Authors: Raman, Ana, Guarraia, Carla, Taliaferro, Dwayne, Stahl, Guillaume, Farabaugh, Philip J.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1484443/
https://ncbi.nlm.nih.gov/pubmed/16682566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.13306
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