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An mRNA sequence derived from a programmed frameshifting signal decreases codon discrimination during translation initiation

Sequences and structures in the mRNA can alter the accuracy of translation. In some cases, mRNA secondary structures like hairpin loops or pseudoknots can cause frequent errors of translational reading frame (programmed frameshifting) or misreading of termination codons as sense (nonsense readthroug...

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Main Authors: Raman, Ana, Guarraia, Carla, Taliaferro, Dwayne, Stahl, Guillaume, Farabaugh, Philip J.
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2006
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1484443/
https://ncbi.nlm.nih.gov/pubmed/16682566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.13306
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