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Versatile derivatisation of solid support media for covalent bonding on DNA-microchips.

A chemistry was developed that permits on DNA-arrays both the covalent immobilisation of pre-fabricated nucleic acids-such as oligonucleotides, PCR-products or peptide nucleic acid oligomers-and the in situ synthesis of such compounds on either glass or polypropylene surfaces. Bonding was found to b...

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Detalhes bibliográficos
Main Authors: Beier, M, Hoheisel, J D
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC148409/
https://ncbi.nlm.nih.gov/pubmed/10198429
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