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Pokeweed antiviral protein cleaves double-stranded supercoiled DNA using the same active site required to depurinate rRNA.

Ribosome-inactivating proteins (RIPs) are N-glycosylases that remove a specific adenine from the sarcin/ricin loop of the large rRNA in a manner analogous to N-glycosylases that are involved in DNA repair. Some RIPs have been reported to remove adenines from single-stranded DNA and cleave double-str...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Principais autores: Wang, P, Tumer, N E
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 1999
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148399/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10101199/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.8.1900
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