Germline polymorphisms in SIPA1 are associated with metastasis and other indicators of poor prognosis in breast cancer

INTRODUCTION: There is growing evidence that heritable genetic variation modulates metastatic efficiency. Our previous work using a mouse mammary tumor model has shown that metastatic efficiency is modulated by the GTPase-activating protein encoded by Sipa1 ('signal-induced proliferation-associ...

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Autors principals: Crawford, Nigel PS, Ziogas, Argyrios, Peel, David J, Hess, James, Anton-Culver, Hoda, Hunter, Kent W
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2006
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1483843/
https://ncbi.nlm.nih.gov/pubmed/16563182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr1389
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