Trans-activation of the Tetrahymena group I intron ribozyme via a non-native RNA-RNA interaction.

The peripheral P2.1 domain of the Tetrahymena group I intron ribozyme has been shown to be non-essential for splicing. We found, however, that separately prepared P2.1 RNA efficiently accelerates the 3' splice-site-specific hydrolysis reaction of a mutant ribozyme lacking both P2.1 and its upst...

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Bibliographic Details
Main Authors: Ikawa, Y, Shiraishi, H, Inoue, T
Format: Artigo
Language:Inglês
Published: 1999
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC148368/
https://ncbi.nlm.nih.gov/pubmed/10075996
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