Multiple oligodeoxyribonucleotide syntheseson a reusable solid-phase CPG support via the hydroquinone-O,O'-diacetic acid (Q-Linker) linker arm.

A strategy for oligodeoxyribonucleotide synthesis on a reusable CPG solid-phase support, derivatized with hydroxyl groups instead of amino groups, has been developed. Ester linkages, through a base labile hydroquinone- O, O '-diacetic acid ( Q-Linker ) linker arm, were used to couple the first nucle...

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Pubblicato in:	Nucleic Acids Res
Autori principali:	Pon, R T, Yu, S, Guo, Z, Sanghvi, Y S
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Oxford University Press 1999
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148349/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10037817/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.6.1531
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