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Mutational analysis of the antigenomic trans-acting delta ribozyme: the alterations of the middle nucleotides located on the P1 stem.

Our previous report on delta ribozyme cleavage using a trans -acting antigenomic delta ribozyme and a collection of short substrates showed that the middle nucleotides of the P1 stem, the substrate binding site, are essential for the cleavage activity. Here we have further investigated the effect of...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Principais autores: Ananvoranich, S, Lafontaine, D A, Perreault, J P
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 1999
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148340/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10037808/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.6.1473
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