hnRNP C and polypyrimidine tract-binding protein specifically interact with the pyrimidine-rich region within the 3'NTR of the HCV RNA genome.

Like other members of the Flaviviridae family, the 3' non-translated region (NTR) of the hepatitis C virus (HCV) is believed to function in the initiation and regulation of viral RNA replication by interacting with components of the viral replicase complex. To inves-tigate the possibility that...

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Bibliographic Details
Main Authors: Gontarek, R R, Gutshall, L L, Herold, K M, Tsai, J, Sathe, G M, Mao, J, Prescott, C, Del Vecchio, A M
Format: Artigo
Language:Inglês
Published: 1999
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC148338/
https://ncbi.nlm.nih.gov/pubmed/10037806
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