Heat shock of HeLa cells inactivates a nuclear protein phosphatase specific for dephosphorylation of the C-terminal domain of RNA polymerase II.

Reversible phosphorylation of the C-terminal domain (CTD) of the largest RNA polymerase II (RNAP II) subunit plays a key role in gene expression. Stresses such as heat shock result in marked changes in CTD phosphorylation as well as in major alterations in gene expression. CTD kinases and CTD phosph...

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Publicat a:	Nucleic Acids Res
Autors principals:	Dubois, M F, Marshall, N F, Nguyen, V T, Dahmus, G K, Bonnet, F, Dahmus, M E, Bensaude, O
Format:	Artigo
Idioma:	Inglês
Publicat:	Oxford University Press 1999
Matèries:	Research Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148321/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9973623/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.5.1338
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