Novel non-isotopic detection of MutY enzyme-recognized mismatches in DNA via ultrasensitive detection of aldehydes.

A highly sensitive method to detect traces of aldehyde-containing apurinic/apyrimidinic (AP) sites in nucleic acids has been developed. Based on this method, a novel approach to detect DNA base mismatches recognized by the mismatch repair glycosylase MutY is demonstrated. Open chain aldehydes genera...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Maulik, G, Botchway, S, Chakrabarti, S, Tetradis, S, Price, B, Makrigiorgos, G M
Формат: Artigo
Язык:Inglês
Опубликовано: 1999
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC148318/
https://ncbi.nlm.nih.gov/pubmed/9973620
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы