The exosome subunit Rrp43p is required for the efficient maturation of 5.8S, 18S and 25S rRNA.

The Saccharomyces cerevisiae protein Rrp43p co-purifies with four other 3'-->5' exoribonucleases in a complex that has been termed the exosome. Rrp43p itself is similar to prokaryotic RNase PH. Individual exosome subunits have been implicated in the 3' maturation of the 5.8S rRNA found in 60S riboso...

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Veröffentlicht in:	Nucleic Acids Res
Hauptverfasser:	Zanchin, N I, Goldfarb, D S
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Oxford University Press 1999
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148313/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9973615/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.5.1283
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