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Involvement of the p97-Ufd1-Npl4 Complex in the Regulated Endoplasmic Reticulum-associated Degradation of Inositol 1,4,5-Trisphosphate Receptors

Inositol 1,4,5-trisphosphate (IP(3)) receptors form tetrameric, IP(3)-gated channels in endoplasmic reticulum membranes that govern the release of Ca(2+) from this organelle. In response to activation of certain G protein-coupled receptors that persistently elevate IP(3) concentration, IP(3) recepto...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Alzayady, Kamil J., Panning, Margaret M., Kelley, Grant G., Wojcikiewicz, Richard J. H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1483127/
https://ncbi.nlm.nih.gov/pubmed/16103111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M508890200
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