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A Computational Protocol for the Integration of the Monotopic Protein Prostaglandin H2 Synthase into a Phospholipid Bilayer
Prostaglandin H2 synthase (PGHS) synthesizes PGH(2), a prostaglandin precursor, from arachidonic acid and was the first monotopic enzyme to have its structure experimentally determined. Both isozymes of PGHS are inhibited by nonsteroidal antiinflammatory drugs, an important class of drugs that are t...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Biophysical Society
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1483072/ https://ncbi.nlm.nih.gov/pubmed/16632499 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.077784 |
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