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Detailed chromosomal and molecular genetic analysis of single cells by whole genome amplification and comparative genomic hybridisation.

Molecular genetic analysis of isolated single cells and other minute DNA samples is limited because there is insufficient DNA to perform more than one independent PCR amplification. One solution to this problem is to first amplify the entire genome, thus providing enough DNA for numerous subsequent...

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Main Authors: Wells, D, Sherlock, J K, Handyside, A H, Delhanty, J D
格式: Artigo
語言:Inglês
出版: 1999
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC148305/
https://ncbi.nlm.nih.gov/pubmed/9927758
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