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Physical State of the Extracellular Matrix Regulates the Structure and Molecular Composition of Cell-Matrix Adhesions

This study establishes that the physical state of the extracellular matrix can regulate integrin-mediated cytoskeletal assembly and tyrosine phosphorylation to generate two distinct types of cell-matrix adhesions. In primary fibroblasts, α(5)β(1) integrin associates mainly with fibronectin fibrils a...

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Bibliographic Details
Main Authors: Katz, Ben-Zion, Zamir, Eli, Bershadsky, Alexander, Kam, Zvi, Yamada, Kenneth M., Geiger, Benjamin
Format: Artigo
Language:Inglês
Published: The American Society for Cell Biology 2000
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC14830/
https://ncbi.nlm.nih.gov/pubmed/10712519
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