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Replication Control of Staphylococcal Multiresistance Plasmid pSK41: an Antisense RNA Mediates Dual-Level Regulation of Rep Expression

Replication of staphylococcal multiresistance plasmid pSK41 is negatively regulated by the antisense transcript RNAI. pSK41 minireplicons bearing rnaI promoter (P(rnaI)) mutations exhibited dramatic increases in copy number, approximately 40-fold higher than the copy number for the wild-type replico...

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Bibliographic Details
Main Authors: Kwong, Stephen M., Skurray, Ronald A., Firth, Neville
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2006
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1482958/
https://ncbi.nlm.nih.gov/pubmed/16740947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00030-06
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