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Ectopic Overexpression of Wild-Type and Mutant hipA Genes in Escherichia coli: Effects on Macromolecular Synthesis and Persister Formation
Persistence is an epigenetic trait that allows a small fraction of bacteria, approximately one in a million, to survive prolonged exposure to antibiotics. In Escherichia coli an increased frequency of persisters, called “high persistence,” is conferred by mutations in the hipA gene, which encodes th...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Microbiology
2006
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1482909/ https://ncbi.nlm.nih.gov/pubmed/16707675 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01740-05 |
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