Heterodimers of the SnoN and Ski oncoproteins form preferentially over homodimers and are more potent transforming agents.

sno is a member of the ski oncogene family and shares ski 's ability to transform avian fibroblasts and induce muscle differentiation. Ski and SnoN are transcription factors that form both homodimers and heterodimers. They recognize a specific DNA binding site (GTCTAGAC) through which they repr...

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Bibliographic Details
Main Authors: Cohen, S B, Zheng, G, Heyman, H C, Stavnezer, E
Format: Artigo
Language:Inglês
Published: 1999
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC148280/
https://ncbi.nlm.nih.gov/pubmed/9927733
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