Ectodysplasin regulates the lymphotoxin-β pathway for hair differentiation

Mutations in the EDA gene cause anhidrotic/hypohidrotic ectodermal dysplasia, a disorder characterized by defective formation of hair, sweat glands, and teeth in humans and in a mouse model, “Tabby” (Ta). The gene encodes ectodysplasin, a TNF ligand family member that activates the NF-κB-signaling p...

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Bibliographic Details
Main Authors: Cui, Chang-Yi, Hashimoto, Tsuyoshi, Grivennikov, Sergei I., Piao, Yulan, Nedospasov, Sergei A., Schlessinger, David
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2006
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1482580/
https://ncbi.nlm.nih.gov/pubmed/16738056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0509678103
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