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An S-nitrosothiol (SNO) synthase function of hemoglobin that utilizes nitrite as a substrate

Red blood cells (RBCs) act as O(2)-responsive transducers of vasodilator and vasoconstrictor activity in lungs and tissues by regulating the availability of nitric oxide (NO). Vasodilation by RBCs is impaired in diseases characterized by hypoxemia. We have proposed that the extent to which RBCs cons...

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Bibliografiske detaljer
Main Authors: Angelo, Michael, Singel, David J., Stamler, Jonathan S.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1482500/
https://ncbi.nlm.nih.gov/pubmed/16717191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0600942103
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