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Regulation of transcription factor latency by receptor-activated proteolysis

The transcription factor Stp1 is endoproteolytically processed in response to extracellular amino acids by the plasma membrane SPS (Ssy1–Ptr3–Ssy5)-sensor. Processed Stp1, lacking a cytoplasmic retention motif, enters the nucleus and induces amino acid transporter gene expression. The SPS-sensor com...

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Autori principali: Andréasson, Claes, Heessen, Stijn, Ljungdahl, Per O.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1482476/
https://ncbi.nlm.nih.gov/pubmed/16778074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.374206
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