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Apurinic/apyrimidinic endonuclease genes from the trypanosomatidae leishmania major and Trypanosoma cruzi confer resistance to oxidizing agents in DNA repair-deficient Escherichia coli.

Apurinic/apyrimidinic (AP) sites in DNA are considered to be highly mutagenic and must be corrected to preserve genetic integrity. We have isolated cDNAs from the Trypanosomatidae Leishmania major and Trypanosoma cruzi capable of complementing the deficiency of exonuclease III and dUTPase in the Esc...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nucleic Acids Res
Egile Nagusiak: Pérez, J, Gallego, C, Bernier-Villamor, V, Camacho, A, González-Pacanowska, D, Ruiz-Pérez, L M
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 1999
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148246/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9889272/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.3.771
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