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A Convenient, General Synthesis of 1,1-Dimethylallyl Esters as Protecting Groups for Carboxylic Acids

[Image: see text] Carboxylic acids were converted in high yield to their 1,1-dimethylallyl (DMA) esters in two steps. Palladium-catalyzed deprotection of DMA esters was shown to be compatible with tert-butyl, benzyl and Fmoc protecting groups, and Fmoc deprotection could be carried out selectively i...

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Autors principals: Sedighi, Minoo, Lipton, Mark A.
Format: Artigo
Idioma:Inglês
Publicat: 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1482401/
https://ncbi.nlm.nih.gov/pubmed/15816730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol0476117
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