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Mass Defect Labeling of Cysteine for Improving Peptide Assignment in Shotgun Proteomic Analyses
A method for improving the identification of peptides in a shotgun proteome analysis using accurate mass measurement has been developed. The improvement is based upon the derivatization of cysteine residues with a novel reagent, 2,4-dibromo-(2′-iodo)acetanilide. The derivitization changes the mass d...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1482400/ https://ncbi.nlm.nih.gov/pubmed/16689545 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac0600407 |
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