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On the metabolism of methylated disulphonamides with a diuretic action—a contribution to the mechanism of action of chlorothiazide and similar compounds
The metabolism of two substances possessing a diuretic action, 4-amino-6-chlorobenzene-1,3-disulphonmethylamide (III) and 6-chloro-3,4-dihydro-2-methyl-7-methylsulphamoyl-2H-1,2,4-benzo[e]thiadiazine-1,1-dioxide (IV), has been studied on rats and human subjects. It has been shown that these compound...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
1962
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1482171/ https://ncbi.nlm.nih.gov/pubmed/14466300 |
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