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Effect of nicotine, nornicotine and allylnornicotine on the diuretic response to water in rats

The LD50 in mice for nicotine, (—)-nornicotine and allylnornicotine given intraperitoneally was respectively 10 mg/kg, 18.8 mg/kg and 93.3 mg/kg. Whilst nicotine inhibited the renal response in rats to water, (—)-nornicotine and allylnornicotine were without effect. Nicotine antidiuresis was not ant...

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Autors principals: Rees, A. H., Schnieden, H.
Format: Artigo
Idioma:Inglês
Publicat: 1962
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1482128/
https://ncbi.nlm.nih.gov/pubmed/14490984
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