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Tissue amine levels and sympathetic blockade after guanethidine and bretylium

A single dose of guanethidine produces a substantial, long-lasting depletion of tissue catecholamines in the rat, whereas a similar dose of bretylium has no effect. Both drugs produce block of the eserine-induced sympathetic pressor effect. Block by guanethidine is induced more rapidly than is amine...

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Detalhes bibliográficos
Main Authors: Cass, Rosemary, Spriggs, T. L. B.
Formato: Artigo
Idioma:Inglês
Publicado em: 1961
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1482083/
https://ncbi.nlm.nih.gov/pubmed/13877106
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