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Detailed analysis of stem I and its 5' and 3' neighbor regions in the trans-acting HDV ribozyme.

To determine the stem I structure of the human hepatitis delta virus (HDV) ribozyme, which is related to the substrate sequence in the trans -acting system, we kinetically studied stem I length and sequences. Stem I extension from 7 to 8 or 9 bp caused a loss of activity and a low amount of active c...

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Bibliographic Details
Main Authors: Nishikawa, F, Roy, M, Fauzi, H, Nishikawa, S
Format: Artigo
Language:Inglês
Published: 1999
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC148193/
https://ncbi.nlm.nih.gov/pubmed/9862958
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